Development of innovative production processes

Production process scaling

Increased oligonucleotide manufacturing capacity

Sylentis will refurbish a new oligonucleotide production plant in Getafe (Madrid) with BREEAM (Building Research Establishment Environmental Assessment Methodology) and GMP building sustainability certification. In addition, it is intended to achieve in the new production plant a reduction of the PMI sustainability parameter to introduce innovative processes in the production plant to ultimately establish a new methodology for the liquid synthesis of oligonucleotides in Sylentis.

Development of innovative production processes

Production process scaling

Increased oligonucleotide manufacturing capacity

Sylentis will refurbish a new oligonucleotide production plant in Getafe (Madrid) with BREEAM (Building Research Establishment Environmental Assessment Methodology) and GMP building sustainability certification. In addition, it is intended to achieve in the new production plant a reduction of the PMI sustainability parameter of at least 10% and to introduce innovative processes in the production plant to ultimately establish a new methodology for the liquid synthesis of oligonucleotides in Sylentis.

Development of innovative production processes

Optimization and improvement, simplification of consumption and development of disruptive processes, among other approaches, in the field of therapeutic oligonucleotides.

Production process scaling

Development, validation and scale-up of manufacturing procedures, as well as sustainable manufacturing for preclinical and clinical trials.

Increased oligonucleotide manufacturing capacity

Rehabilitation of a new sustainable plant with flexible capacity to manufacture and supply RNA therapeutics.